Endocrine Abstracts

To examine use of I131 therapy we conducted a retrospective analysis of patient case notes that received I131 between May 2002 and Dec 2003.46 patients received radioiodine therapy during 18 months. All had a prior thyroid uptake scan confirming their diagnosis and written informed consent obtained.Results: GD: 29 patients (18F:11M; aged 52.6±2.8 yrs). 11 had a FT3 of <10 pmol/L pre radioiodine...

Autoimmune thyroid diseases (AITD), Graves’ disease (GD) and Hashimoto’s thyroiditis (HT) cluster in families. We investigated whether having a family history (FH) of AITD altered age of diagnosis. The cohort comprised 2296 GD (1920F,376M) and 361 HT (313F,48M) recruited according to standard diagnostic criteria. We compared age at diagnosis of GD or HT in those with or without a FH of overt hyper- or hypothyroidism (ascertained using a standardised questionnaire).</...

The association of autoimmune thyroid diseases (AITD) with other autoimmune disorders is well documented. Familial prevalence of thyroid dysfunction and other autoimmune diseases was examined in our cohort of 2296 with Graves’ disease (GD) (1920 females, 376 males) and 361 with Hashimoto’s thyroiditis (HT) (313 females, 48 males), probands being recruited using standard diagnostic criteria. FH was ascertained using a standardised structured questionnaire.<p class...